<html><head><meta http-equiv="Content-Type" content="text/html charset=utf-8"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" class="">Everyone<div class=""><br class=""></div><div class="">Bad news, looks like we need to back to the drawing board! </div><div class=""><br class=""></div><div class="">Let’s meet to discuss the next steps. </div><div class=""><br class=""></div><div class="">Thanks for all of your efforts so far. I am not giving up! </div><div class=""><br class=""></div><div class="">Andrew<br class=""><div><br class=""><blockquote type="cite" class=""><div class="">Begin forwarded message:</div><br class="Apple-interchange-newline"><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px;" class=""><span style="font-family: -webkit-system-font, Helvetica Neue, Helvetica, sans-serif; color:rgba(0, 0, 0, 1.0);" class=""><b class="">From: </b></span><span style="font-family: -webkit-system-font, Helvetica Neue, Helvetica, sans-serif;" class="">"Balkin, Ethan R." <<a href="mailto:Ethan.Balkin@science.doe.gov" class="">Ethan.Balkin@science.doe.gov</a>><br class=""></span></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px;" class=""><span style="font-family: -webkit-system-font, Helvetica Neue, Helvetica, sans-serif; color:rgba(0, 0, 0, 1.0);" class=""><b class="">Subject: </b></span><span style="font-family: -webkit-system-font, Helvetica Neue, Helvetica, sans-serif;" class=""><b class="">Isotope Production Proposal at JLAB's LERF Facility...</b><br class=""></span></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px;" class=""><span style="font-family: -webkit-system-font, Helvetica Neue, Helvetica, sans-serif; color:rgba(0, 0, 0, 1.0);" class=""><b class="">Date: </b></span><span style="font-family: -webkit-system-font, Helvetica Neue, Helvetica, sans-serif;" class="">April 16, 2016 at 11:49:29 AM EDT<br class=""></span></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px;" class=""><span style="font-family: -webkit-system-font, Helvetica Neue, Helvetica, sans-serif; color:rgba(0, 0, 0, 1.0);" class=""><b class="">To: </b></span><span style="font-family: -webkit-system-font, Helvetica Neue, Helvetica, sans-serif;" class="">"'Hutton Andrew'" <<a href="mailto:andrew@jlab.org" class="">andrew@jlab.org</a>><br class=""></span></div><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px;" class=""><span style="font-family: -webkit-system-font, Helvetica Neue, Helvetica, sans-serif; color:rgba(0, 0, 0, 1.0);" class=""><b class="">Cc: </b></span><span style="font-family: -webkit-system-font, Helvetica Neue, Helvetica, sans-serif;" class="">"Gillo, Jehanne" <<a href="mailto:Jehanne.Gillo@science.doe.gov" class="">Jehanne.Gillo@science.doe.gov</a>>, "Garland, Marc" <<a href="mailto:Marc.Garland@science.doe.gov" class="">Marc.Garland@science.doe.gov</a>>, "Phillips, Dennis" <<a href="mailto:Dennis.Phillips@science.doe.gov" class="">Dennis.Phillips@science.doe.gov</a>>, "Romero, Luisa" <<a href="mailto:Luisa.Romero@science.doe.gov" class="">Luisa.Romero@science.doe.gov</a>><br class=""></span></div><br class=""><div class=""><div class="WordSection1" style="page: WordSection1; font-family: Helvetica; font-size: 14px; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-stroke-width: 0px;"><p class="MsoNormalCxSpFirst" style="margin-bottom: 0.0001pt; line-height: normal;">Dear Dr. Hutton,<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;"><o:p class=""> </o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">We considered your proposal addressing “Isotope Production at the Jefferson Lab LERF Facility”. Unfortunately, in its present form, we cannot support this proposal. We are concerned with the proposed target design and the lack of cost-effective production.<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;"><o:p class=""> </o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">The technical expertise of the J-Lab investigators is unquestionable. Additionally, J-Lab has unique resources that could be leveraged to advance the DoE Isotope Program’s production efforts. However, the particular target design chosen (liquid Ga metal) is a technically challenging approach for facilities which routinely conduct isotope production; let alone one attempting it for the first time. It is not clear that the design complexity, as it directly relates to isotopic production and radiochemical separation, has been taken into consideration. If a liquid metal target is something that you wish to pursue, I encourage you to seek funding in one of the competitive isotope production R&D FOAs administered by Dennis Phillips (there is one that will be advertised in the very near future). However, if routine integration into the isotope production complex is what you seek, I would encourage you to consider redesigning your target to improve the radiochemical yield obtained per-hour of irradiation while significantly reducing the per-unit cost of production/isolation, and/or identify alternative isotopes which might afford you those production characteristics. Just to let you know, the current proposed costs are more than an order of magnitude too high for cost effective routine production. <span class="Apple-converted-space"> </span><o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;"><o:p class=""> </o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">For reference, please see the 2015 NSAC-I committee report to identify alternative isotopes in demand by the user community.<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;"><o:p class=""> </o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">Thank you again for your proposal and we look forward to considering a revised version.<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;"><o:p class=""> </o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">Best regards,<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">-Ethan<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">____________________________________<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">Dr. Ethan R. Balkin<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">Isotope Production Facilities Program Manager<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">U.S. Department of Energy Isotope Program<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">Office of Science: Office of Nuclear Physics<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">Germantown Building, SC-26.2<span class="Apple-converted-space"> </span><br class="">1000 Independence Ave., SW<span class="Apple-converted-space"> </span><o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">Washington, DC 20585-1290<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">Phone: (301)903-1861<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">Fax: (301)903-3833<o:p class=""></o:p></p><p class="MsoNormalCxSpMiddle" style="margin-bottom: 0.0001pt; line-height: normal;">Email:<span class="Apple-converted-space"> </span><a href="mailto:ethan.balkin@science.doe.gov" style="color: purple; text-decoration: underline;" class=""><span style="color: blue;" class="">ethan.balkin@science.doe.gov</span></a><o:p class=""></o:p></p><p class="MsoNormal" style="margin: 0in 0in 8pt; line-height: 16.959999084472656px; font-size: 12pt; font-family: Arial, sans-serif;"><img class="" apple-inline="yes" id="D49B666A-E52D-474E-BCF1-CE2AE47E63CA" height="34" width="191" apple-width="yes" apple-height="yes" src="cid:image001.jpg@01D197D6.08920D80"></p></div></div></blockquote></div><br class=""></div></body></html>