<html><body><div style="font-family: arial, helvetica, sans-serif; font-size: 12pt; color: #000000"><div>I have updated two sections at the end of the narrative.</div><div>It is in the dropbox folder 24June2016 and later. The name</div><div>is 26June2016 draft narrative.</div><div><br></div><div>Section on objectives - rearranged the items.</div><div><br data-mce-bogus="1"></div><div>Elaborated the summary to ensure that the elements mentioned in the FOA</div><div>are addressed. You may want to elaborate. </div><div><br data-mce-bogus="1"></div><div>-H</div><div><br data-mce-bogus="1"></div><div>The elements are:</div><div><br data-mce-bogus="1"></div><div><br data-mce-bogus="1"></div><div><ul><li data-mce-style="margin: 0px;" style="margin: 0px;">clearly describe how the outcome would support and enhance the production of isotopes used for research and applications in medicine, homeland security, the physical sciences, biological and geological sciences, energy, industry, etc.</li><li data-mce-style="margin: 0px;" style="margin: 0px;">incorporate effective ways to train personnel with essential knowledge and skills related to the production, processing, purification, and distribution of enriched stable and radioactive isotopes</li><li style="text-indent: -.25in;" data-mce-style="text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Novel or improved capabilities for inducing transmutation of atoms in targets to create radioisotopes;</li><li style="text-indent: -.25in;" data-mce-style="text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Optimum selection of the materials and effective design of targets for the production of radioisotopes;</li><li style="text-indent: -.25in;" data-mce-style="text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Innovative approaches to model and predict behavior of targets undergoing irradiation in order to optimize yield and minimize target failures during routine isotope production;</li><li style="text-indent: -.25in;" data-mce-style="text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Chemical and physical processes to recover and purify radioisotopes from activated targets, legacy materials, or facility components;</li><li style="text-indent: -.25in;" data-mce-style="text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Automation of production and processing techniques to enhance efficiency and safety of the production of radioisotopes; and</li><li style="text-indent: -.25in;" data-mce-style="text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Mass-separation for enriched stable isotopes and high specific activity radioactive isotopes</li></ul><p style="margin: 0px;" data-mce-style="margin: 0px;"> </p><p style="margin: 0px;" data-mce-style="margin: 0px;">Merit Review Criteria</p><p style="margin: 0px;" data-mce-style="margin: 0px;">` Scientific and/or Technical Merit of the Project;</p><ul><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>What is the scientific innovation of proposed research?</li><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>What is the likelihood of achieving valuable results?</li><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>How might the results of the proposed work impact the direction, progress, and thinking in relevant scientific fields of research?</li><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>How does the proposed work compare with other efforts in its field, both in terms of scientific and/or technical merit and originality?</li><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Is the Data Management Plan suitable for the proposed research and to what extent does it support the validation of research results?</li></ul><p style="margin: 0px;" data-mce-style="margin: 0px;"> </p><p style="text-indent: 0.5in; margin: 0px;" data-mce-style="text-indent: 0.5in; margin: 0px;">Appropriateness of the Proposed Method or Approach;</p><ul><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>How logical and feasible are the research approaches?</li><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Does the proposed research employ innovative concepts or methods?</li><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Are the conceptual framework, methods, and analyses well justified, adequately developed, and likely to lead to scientifically valid conclusions?</li><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Does the applicant recognize significant potential problems and consider alternative strategies?</li></ul><p style="margin: 0px;" data-mce-style="margin: 0px;"> </p><p style="text-indent: 0.5in; margin: 0px;" data-mce-style="text-indent: 0.5in; margin: 0px;">Competency of Applicant’s Personnel and Adequacy of Proposed Resources</p><ul><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>What is the past performance and potential of the Principal Investigator (PI)?</li><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>How well qualified is the research team to carry out the proposed research?</li><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Are the research environment and facilities adequate for performing the research?</li><li style="margin-left: .75in; text-indent: -.25in;" data-mce-style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;" data-mce-style="font-family: Symbol;"><span style="font: 7.0pt 'Times New Roman';" data-mce-style="font: 7.0pt 'Times New Roman';"> </span></span>Does the proposed work take advantage of unique facilities and capabilities?</li></ul><p style="text-indent: 0.5in; margin: 0px;" data-mce-style="text-indent: 0.5in; margin: 0px;"> </p><p style="text-indent: 0.5in; margin: 0px;" data-mce-style="text-indent: 0.5in; margin: 0px;"><br></p></div></div></body></html>