<html><body><div style="font-family: arial, helvetica, sans-serif; font-size: 12pt; color: #000000"><div>Dear Pavel,<br></div><div>Thanks for the input.<br data-mce-bogus="1"></div><div><br data-mce-bogus="1"></div><div>You are absolutely right abouth hBN, I will add to the narrative,<br data-mce-bogus="1"></div><div>we do not know what radiation does to hBN's integrity and its<br></div><div>properties (thermal conductivity). That is another piece of data<br></div><div>that will result from this R&D. If hBN fails, we have a fall back<br data-mce-bogus="1"></div><div>in ceramic insert. <br data-mce-bogus="1"></div><div><br data-mce-bogus="1"></div><div>Two more things that you can shed light on.<br data-mce-bogus="1"></div><div><br data-mce-bogus="1"></div><div>We claim that low energy tests at LERF will eliminate or reduce<br data-mce-bogus="1"></div><div>local activity. Keeping to around 6 MeV will help with tungsten<br data-mce-bogus="1"></div><div>and copper. Is this true for Be and BN?<br data-mce-bogus="1"></div><div><br data-mce-bogus="1"></div><div><br data-mce-bogus="1"></div><div>Thanks.<br data-mce-bogus="1"></div><div><br data-mce-bogus="1"></div><div>-H<br data-mce-bogus="1"></div><div><br></div><div><br></div><hr id="zwchr" data-marker="__DIVIDER__"><div data-marker="__HEADERS__"><b>From: </b>"Pavel Degtiarenko" <pavel@jlab.org><br><b>To: </b>"isotope-prod" <isotope-prod@jlab.org><br><b>Sent: </b>Sunday, June 26, 2016 6:50:08 PM<br><b>Subject: </b>Re: [Isotope-prod] Updated draft narrative<br></div><div><br></div><div data-marker="__QUOTED_TEXT__"><div class="moz-cite-prefix">Dear Hari,<br>
<br>
Several remarks:<br>
1. On pages 3 and 4 the subtitle <span style="color: #ff0000;" data-mce-style="color: #ff0000;" color="#ff0000">"</span>
<i style="mso-bidi-font-style:
normal"><span style="text-decoration: underline;" data-mce-style="text-decoration: underline;"><span style="font-family:"Times New
Roman";mso-fareast-font-family:
"Times New Roman";mso-ansi-language:EN-GB" lang="EN-GB"><span style="color: #ff0000;" data-mce-style="color: #ff0000;" color="#ff0000">Photo-production
Principles"</span> </span></span></i>is repeated twice. The
second one should probably be "
<i style="mso-bidi-font-style:
normal"><span style="text-decoration: underline;" data-mce-style="text-decoration: underline;"><span style="font-family:"Times New
Roman";mso-fareast-font-family:
"Times New Roman";mso-ansi-language:EN-GB" lang="EN-GB">Photo-production Process"</span></span></i><br>
<br>
2. On page 5 the typos are is in the reaction description (67
should be superscript, and the reaction should be "gamma,alpha"):<br>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt"><span style="color: #ff0000;" data-mce-style="color: #ff0000;" color="#ff0000"><span style="font-family:"Times New
Roman";mso-ansi-language:EN-GB" lang="EN-GB">"Similarly,
67Cu can be produced via the <sup>71</sup>Ga (</span><span style="font-family:Symbol;mso-ansi-language:EN-GB" lang="EN-GB">g</span></span><span style="font-family:"Times New
Roman";mso-ansi-language:EN-GB" lang="EN-GB"><span style="color: #ff0000;" data-mce-style="color: #ff0000;" color="#ff0000">, p) <sup>67</sup>Cu
reaction, as in this proposal."</span></span></p>
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3. Page 8, last line needs the dot at the end:
<p class="MsoNormal" style="text-align:justify"><span style="font-family:"Times New Roman""><span style="color: #ff0000;" data-mce-style="color: #ff0000;" color="#ff0000">"including
studies of targeted hybrid probes"</span></span></p>
4. Page 16, discussion of the parasitic test at 10 MeV, the
statement <br>
<p class="MsoNormal" style="text-align:justify"><span style="font-family:"Times New Roman""><span style="color: #ff0000;" data-mce-style="color: #ff0000;" color="#ff0000">"This
is not a surprising result because the energy threshold for
production is
higher."</span></span><br>
</p>
should be "This is not a surprising result because while the beam
energy is above the production threshold, the cross section for
the alpha particle emission is suppressed by the nuclear Coulomb
barrier."<br>
<br>
5. Page 17, correct <span style="color: #ff0000;" data-mce-style="color: #ff0000;" color="#ff0000">"<span style="font-size:11.0pt;line-height:115%;
font-family:"Times New
Roman";mso-fareast-font-family:Calibri;mso-ansi-language:
EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">stay
below the <sup>69</sup>Ga(</span><span style="font-size:11.0pt;line-height:115%;font-family:Symbol;mso-ascii-font-family:"Times
New
Roman";mso-fareast-font-family:Calibri;mso-hansi-font-family:"Times
New Roman";
mso-bidi-font-family:"Times New
Roman";mso-ansi-language:EN-US;mso-fareast-language:
EN-US;mso-bidi-language:AR-SA;mso-char-type:symbol;mso-symbol-font-family:Symbol"><span style="mso-char-type:symbol;mso-symbol-font-family:Symbol">g</span></span><span style="font-size:11.0pt;line-height:115%;font-family:"Times New
Roman";
mso-fareast-font-family:Calibri;mso-ansi-language:EN-US;mso-fareast-language:
EN-US;mso-bidi-language:AR-SA">, 2n)<sup>67</sup>Ga <span style="mso-spacerun:yes"> </span>because </span>"</span>
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<span style="font-size:11.0pt;line-height:115%;
font-family:"Times New
Roman";mso-fareast-font-family:Calibri;mso-ansi-language:
EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">stay
below the <sup>69</sup>Ga(</span><span style="font-size:11.0pt;line-height:115%;font-family:Symbol;mso-ascii-font-family:"Times
New
Roman";mso-fareast-font-family:Calibri;mso-hansi-font-family:"Times
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mso-bidi-font-family:"Times New
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EN-US;mso-bidi-language:AR-SA;mso-char-type:symbol;mso-symbol-font-family:Symbol"><span style="mso-char-type:symbol;mso-symbol-font-family:Symbol">g</span></span><span style="font-size:11.0pt;line-height:115%;font-family:"Times
New Roman";
mso-fareast-font-family:Calibri;mso-ansi-language:EN-US;mso-fareast-language:
EN-US;mso-bidi-language:AR-SA">, 2n)<sup>67</sup>Ga <span style="mso-spacerun:yes"></span><span style="color: #3333ff;" data-mce-style="color: #3333ff;" color="#3333ff">reaction
threshold</span> because </span>
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<br>
<br>
6. I think that at present we don't really have a proof that hBN
target holder will perform as we say it will. One of the questions
to be answered by the tests is how well this material will
withstand the radiation damage. We know that chemical structure of
hBN is close to graphite. There are studies on the rad. damage to
graphite, causing displacements in the crystal structure and loss
of thermal conductivity. I think we should mention somewhere that
we know about the issue, will do dedicated testing, and will
consider alternatives if hBN won't work.<br>
<br>
Best regards,<br>
Pavel<br>
<br>
On 6/26/2016 4:28 PM, Hari Areti wrote:<br>
</div>
<blockquote cite="mid:349803214.3015668.1466972936246.JavaMail.zimbra@jlab.org">
<div style="font-family: arial, helvetica, sans-serif; font-size:
12pt; color: #000000">
<div>I have updated two sections at the end of the narrative.</div>
<div>It is in the dropbox folder 24June2016 and later. The name</div>
<div>is 26June2016 draft narrative.</div>
<div><br>
</div>
<div>Section on objectives - rearranged the items.</div>
<div><br>
</div>
<div>Elaborated the summary to ensure that the elements
mentioned in the FOA</div>
<div>are addressed. You may want to elaborate. </div>
<div><br>
</div>
<div>-H</div>
<div><br>
</div>
<div>The elements are:</div>
<div><br>
</div>
<div><br>
</div>
<div>
<ul>
<li style="margin: 0px;">clearly
describe how the outcome would support and enhance the
production of isotopes used for research and applications
in medicine, homeland security, the physical sciences,
biological and geological sciences, energy, industry, etc.</li>
<li style="margin: 0px;">incorporate
effective ways to train personnel with essential knowledge
and skills related to the production, processing,
purification, and distribution of enriched stable and
radioactive isotopes</li>
<li style="text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Novel or
improved capabilities for inducing transmutation of atoms
in targets to create radioisotopes;</li>
<li style="text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Optimum
selection of the materials and effective design of targets
for the production of radioisotopes;</li>
<li style="text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Innovative
approaches to model and predict behavior of targets
undergoing irradiation in order to optimize yield and
minimize target failures during routine isotope
production;</li>
<li style="text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Chemical
and physical processes to recover and purify radioisotopes
from activated targets, legacy materials, or facility
components;</li>
<li style="text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Automation
of production and processing techniques to enhance
efficiency and safety of the production of radioisotopes;
and</li>
<li style="text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Mass-separation
for enriched stable isotopes and high specific activity
radioactive isotopes</li>
</ul>
<p style="margin: 0px;"> </p>
<p style="margin: 0px;">Merit
Review Criteria</p>
<p style="margin: 0px;">`
Scientific and/or Technical Merit of the Project;</p>
<ul>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>What is
the scientific innovation of proposed research?</li>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>What is
the likelihood of achieving valuable results?</li>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>How might
the results of the proposed work impact the direction,
progress, and thinking in relevant scientific fields of
research?</li>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>How does
the proposed work compare with other efforts in its field,
both in terms of scientific and/or technical merit and
originality?</li>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Is the
Data Management Plan suitable for the proposed research
and to what extent does it support the validation of
research results?</li>
</ul>
<p style="margin: 0px;"> </p>
<p style="text-indent: 0.5in; margin: 0px;">Appropriateness
of the Proposed Method or Approach;</p>
<ul>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>How
logical and feasible are the research approaches?</li>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Does the
proposed research employ innovative concepts or methods?</li>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Are the
conceptual framework, methods, and analyses well
justified, adequately developed, and likely to lead to
scientifically valid conclusions?</li>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Does the
applicant recognize significant potential problems and
consider alternative strategies?</li>
</ul>
<p style="margin: 0px;"> </p>
<p style="text-indent: 0.5in; margin: 0px;">Competency
of Applicant’s Personnel and Adequacy of Proposed Resources</p>
<ul>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>What is
the past performance and potential of the Principal
Investigator (PI)?</li>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>How well
qualified is the research team to carry out the proposed
research?</li>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Are the
research environment and facilities adequate for
performing the research?</li>
<li style="margin-left: .75in; text-indent: -.25in;"><span style="font-family: Symbol;"><span style="font:
7.0pt 'Times New Roman';"> </span></span>Does the
proposed work take advantage of unique facilities and
capabilities?</li>
</ul>
<p style="text-indent: 0.5in; margin: 0px;"> </p>
<p style="text-indent: 0.5in; margin: 0px;"><br>
</p>
</div>
</div>
<br>
<fieldset class="mimeAttachmentHeader"></fieldset>
<br>
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</blockquote>
<p><br>
</p>
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