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    <div class="moz-cite-prefix">Dear Hari,<br>
      <br>
      We will see some indirect activation by neutrons from the
      Be-9(gamma,n)Be-8 reaction, where the threshold is low (1.665
      MeV). Be-8 decays to 2 alphas.<br>
      <br>
      There will be no Be-7 production up to ~20 MeV.<br>
      <br>
      B-10(gamma,n)B-9 threshold is 8.437 MeV; B-9 decays immediately to
      Be-9 - no long lived isotopes.<br>
      <br>
      N-14(gamma,n)N-13 threshold is just above 10 MeV, so no production
      there. But at higher energy that will produce a lot of short-lived
      activity (~10 min half lifetime).<br>
      <br>
      If we limit the beam energy at 6 MeV the only source of activation
      will be indirect neutrons from the Be-9(gamma,n)Be-8 reaction.  I
      do not expect a problem here, but it should be evaluated before
      planning the tests. <br>
      <br>
      Best regards,<br>
      Pavel<br>
      <br>
      <br>
      <br>
      On 06/27/2016 08:35 AM, Hari Areti wrote:<br>
    </div>
    <blockquote
      cite="mid:1635631830.3123476.1467030935196.JavaMail.zimbra@jlab.org"
      type="cite">
      <div style="font-family: arial, helvetica, sans-serif; font-size:
        12pt; color: #000000">
        <div>Dear Pavel,<br>
        </div>
        <div>Thanks for the input.<br data-mce-bogus="1">
        </div>
        <div><br data-mce-bogus="1">
        </div>
        <div>You are absolutely right abouth hBN, I will add to the
          narrative,<br data-mce-bogus="1">
        </div>
        <div>we do not know what radiation does to hBN's integrity and
          its<br>
        </div>
        <div>properties (thermal conductivity). That is another piece of
          data<br>
        </div>
        <div>that will result from this R&D. If hBN fails, we have a
          fall back<br data-mce-bogus="1">
        </div>
        <div>in ceramic insert. <br data-mce-bogus="1">
        </div>
        <div><br data-mce-bogus="1">
        </div>
        <div>Two more things that you can shed light on.<br
            data-mce-bogus="1">
        </div>
        <div><br data-mce-bogus="1">
        </div>
        <div>We claim that low energy tests at LERF will eliminate or
          reduce<br data-mce-bogus="1">
        </div>
        <div>local activity. Keeping to around 6 MeV will help with
          tungsten<br data-mce-bogus="1">
        </div>
        <div>and copper. Is this true for Be and BN?<br
            data-mce-bogus="1">
        </div>
        <div><br data-mce-bogus="1">
        </div>
        <div><br data-mce-bogus="1">
        </div>
        <div>Thanks.<br data-mce-bogus="1">
        </div>
        <div><br data-mce-bogus="1">
        </div>
        <div>-H<br data-mce-bogus="1">
        </div>
        <div><br>
        </div>
        <div><br>
        </div>
        <hr id="zwchr" data-marker="__DIVIDER__">
        <div data-marker="__HEADERS__"><b>From: </b>"Pavel Degtiarenko"
          <a class="moz-txt-link-rfc2396E" href="mailto:pavel@jlab.org"><pavel@jlab.org></a><br>
          <b>To: </b>"isotope-prod" <a class="moz-txt-link-rfc2396E" href="mailto:isotope-prod@jlab.org"><isotope-prod@jlab.org></a><br>
          <b>Sent: </b>Sunday, June 26, 2016 6:50:08 PM<br>
          <b>Subject: </b>Re: [Isotope-prod] Updated draft narrative<br>
        </div>
        <div><br>
        </div>
        <div data-marker="__QUOTED_TEXT__">
          <div class="moz-cite-prefix">Dear Hari,<br>
            <br>
            Several remarks:<br>
            1. On pages 3 and 4 the subtitle <span style="color:
              #ff0000;" data-mce-style="color: #ff0000;" color="#ff0000">"</span>
            <i style="mso-bidi-font-style: normal"><span
                style="text-decoration: underline;"
                data-mce-style="text-decoration: underline;"><span
                  style="font-family:"Times New
                  Roman";mso-fareast-font-family: "Times New
                  Roman";mso-ansi-language:EN-GB" lang="EN-GB"><span
                    style="color: #ff0000;" data-mce-style="color:
                    #ff0000;" color="#ff0000">Photo-production
                    Principles"</span> </span></span></i>is repeated
            twice. The second one should probably be " <i
              style="mso-bidi-font-style: normal"><span
                style="text-decoration: underline;"
                data-mce-style="text-decoration: underline;"><span
                  style="font-family:"Times New
                  Roman";mso-fareast-font-family: "Times New
                  Roman";mso-ansi-language:EN-GB" lang="EN-GB">Photo-production
                  Process"</span></span></i><br>
            <br>
            2. On page 5 the typos are is in the reaction description
            (67 should be superscript, and the reaction should be
            "gamma,alpha"):<br>
            <p class="MsoNormal"
              style="margin-bottom:0in;margin-bottom:.0001pt"><span
                style="color: #ff0000;" data-mce-style="color: #ff0000;"
                color="#ff0000"><span style="font-family:"Times New
                  Roman";mso-ansi-language:EN-GB" lang="EN-GB">"Similarly,

                  67Cu can be produced via the <sup>71</sup>Ga (</span><span
                  style="font-family:Symbol;mso-ansi-language:EN-GB"
                  lang="EN-GB">g</span></span><span
                style="font-family:"Times New
                Roman";mso-ansi-language:EN-GB" lang="EN-GB"><span
                  style="color: #ff0000;" data-mce-style="color:
                  #ff0000;" color="#ff0000">, p) <sup>67</sup>Cu
                  reaction, as in this proposal."</span></span></p>
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            3. Page 8, last line needs the dot at the end:
            <p class="MsoNormal" style="text-align:justify"><span
                style="font-family:"Times New Roman""><span
                  style="color: #ff0000;" data-mce-style="color:
                  #ff0000;" color="#ff0000">"including studies of
                  targeted hybrid probes"</span></span></p>
            4. Page 16, discussion of the parasitic test at 10 MeV, the
            statement <br>
            <p class="MsoNormal" style="text-align:justify"><span
                style="font-family:"Times New Roman""><span
                  style="color: #ff0000;" data-mce-style="color:
                  #ff0000;" color="#ff0000">"This is not a surprising
                  result because the energy threshold for production is
                  higher."</span></span><br>
            </p>
            should be "This is not a surprising result because while the
            beam energy is above the production threshold, the cross
            section for the alpha particle emission is suppressed by the
            nuclear Coulomb barrier."<br>
            <br>
            5.  Page 17, correct <span style="color: #ff0000;"
              data-mce-style="color: #ff0000;" color="#ff0000">"<span
                style="font-size:11.0pt;line-height:115%;
                font-family:"Times New
                Roman";mso-fareast-font-family:Calibri;mso-ansi-language:
EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">stay below the
                <sup>69</sup>Ga(</span><span
                style="font-size:11.0pt;line-height:115%;font-family:Symbol;mso-ascii-font-family:"Times

                New
                Roman";mso-fareast-font-family:Calibri;mso-hansi-font-family:"Times

                New Roman"; mso-bidi-font-family:"Times New
                Roman";mso-ansi-language:EN-US;mso-fareast-language:
EN-US;mso-bidi-language:AR-SA;mso-char-type:symbol;mso-symbol-font-family:Symbol"><span
style="mso-char-type:symbol;mso-symbol-font-family:Symbol">g</span></span><span
                style="font-size:11.0pt;line-height:115%;font-family:"Times
                New Roman";
                mso-fareast-font-family:Calibri;mso-ansi-language:EN-US;mso-fareast-language:

                EN-US;mso-bidi-language:AR-SA">, 2n)<sup>67</sup>Ga <span
                  style="mso-spacerun:yes"> </span>because </span>"</span>
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</style> to " <span style="font-size:11.0pt;line-height:115%;
              font-family:"Times New
              Roman";mso-fareast-font-family:Calibri;mso-ansi-language:
              EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA">stay

              below the <sup>69</sup>Ga(</span><span
              style="font-size:11.0pt;line-height:115%;font-family:Symbol;mso-ascii-font-family:"Times

              New
              Roman";mso-fareast-font-family:Calibri;mso-hansi-font-family:"Times

              New Roman"; mso-bidi-font-family:"Times New
              Roman";mso-ansi-language:EN-US;mso-fareast-language:
EN-US;mso-bidi-language:AR-SA;mso-char-type:symbol;mso-symbol-font-family:Symbol"><span
style="mso-char-type:symbol;mso-symbol-font-family:Symbol">g</span></span><span
              style="font-size:11.0pt;line-height:115%;font-family:"Times

              New Roman";
              mso-fareast-font-family:Calibri;mso-ansi-language:EN-US;mso-fareast-language:

              EN-US;mso-bidi-language:AR-SA">, 2n)<sup>67</sup>Ga  <span
                style="mso-spacerun:yes"></span><span style="color:
                #3333ff;" data-mce-style="color: #3333ff;"
                color="#3333ff">reaction threshold</span> because </span>
            <style>
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</style>"<br>
            <br>
            <br>
            6.  I think that at present we don't really have a proof
            that hBN target holder will perform as we say it will. One
            of the questions to be answered by the tests is how well
            this material will withstand the radiation damage. We know
            that chemical structure of hBN is close to graphite. There
            are studies on the rad. damage to graphite, causing
            displacements in the crystal structure and loss of thermal
            conductivity. I think we should mention somewhere that we
            know about the issue, will do dedicated testing, and will
            consider alternatives if hBN won't work.<br>
            <br>
            Best regards,<br>
            Pavel<br>
            <br>
            On 6/26/2016 4:28 PM, Hari Areti wrote:<br>
          </div>
          <blockquote
            cite="mid:349803214.3015668.1466972936246.JavaMail.zimbra@jlab.org">
            <div style="font-family: arial, helvetica, sans-serif;
              font-size: 12pt; color: #000000">
              <div>I have updated two sections at the end of the
                narrative.</div>
              <div>It is in the dropbox folder 24June2016 and later. The
                name</div>
              <div>is 26June2016 draft narrative.</div>
              <div><br>
              </div>
              <div>Section on objectives - rearranged the items.</div>
              <div><br>
              </div>
              <div>Elaborated the summary to ensure that the elements
                mentioned in the FOA</div>
              <div>are addressed. You may want to elaborate. </div>
              <div><br>
              </div>
              <div>-H</div>
              <div><br>
              </div>
              <div>The elements are:</div>
              <div><br>
              </div>
              <div><br>
              </div>
              <div>
                <ul>
                  <li style="margin: 0px;">clearly describe how the
                    outcome  would support and enhance the production of
                    isotopes used for research and applications in
                    medicine, homeland security, the physical sciences,
                    biological and geological sciences, energy,
                    industry, etc.</li>
                  <li style="margin: 0px;">incorporate effective ways to
                    train personnel with essential knowledge and skills
                    related to the production, processing, purification,
                    and distribution of enriched stable and radioactive
                    isotopes</li>
                  <li style="text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Novel
                    or improved capabilities for inducing transmutation
                    of atoms in targets to create radioisotopes;</li>
                  <li style="text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Optimum

                    selection of the materials and effective design of
                    targets for the production of radioisotopes;</li>
                  <li style="text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Innovative

                    approaches to model and predict behavior of targets
                    undergoing irradiation in order to optimize yield
                    and minimize target failures during routine isotope
                    production;</li>
                  <li style="text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Chemical

                    and physical processes to recover and purify
                    radioisotopes from activated targets, legacy
                    materials, or facility components;</li>
                  <li style="text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Automation

                    of production and processing techniques to enhance
                    efficiency and safety of the production of
                    radioisotopes; and</li>
                  <li style="text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Mass-separation

                    for enriched stable isotopes and high specific
                    activity radioactive isotopes</li>
                </ul>
                <p style="margin: 0px;"> </p>
                <p style="margin: 0px;">Merit Review Criteria</p>
                <p style="margin: 0px;">`               Scientific
                  and/or Technical Merit of the Project;</p>
                <ul>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>What
                    is the scientific innovation of proposed research?</li>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>What
                    is the likelihood of achieving valuable results?</li>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>How
                    might the results of the proposed work impact the
                    direction, progress, and thinking in relevant
                    scientific fields of research?</li>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>How
                    does the proposed work compare with other efforts in
                    its field, both in terms of scientific and/or
                    technical merit and originality?</li>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Is
                    the Data Management Plan suitable for the proposed
                    research and to what extent does it support the
                    validation of research results?</li>
                </ul>
                <p style="margin: 0px;"> </p>
                <p style="text-indent: 0.5in; margin: 0px;">Appropriateness

                  of the Proposed Method or Approach;</p>
                <ul>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>How

                    logical and feasible are the research approaches?</li>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Does
                    the proposed research employ innovative concepts or
                    methods?</li>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Are
                    the conceptual framework, methods, and analyses well
                    justified, adequately developed, and likely to lead
                    to scientifically valid conclusions?</li>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Does
                    the applicant recognize significant potential
                    problems and consider alternative strategies?</li>
                </ul>
                <p style="margin: 0px;"> </p>
                <p style="text-indent: 0.5in; margin: 0px;">Competency
                  of Applicant’s Personnel and Adequacy of Proposed
                  Resources</p>
                <ul>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>What
                    is the past performance and potential of the
                    Principal Investigator (PI)?</li>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>How
                    well qualified is the research team to carry out the
                    proposed research?</li>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Are
                    the research environment and facilities adequate for
                    performing the research?</li>
                  <li style="margin-left: .75in; text-indent: -.25in;"><span
                      style="font-family: Symbol;"><span style="font:
                        7.0pt 'Times New Roman';">         </span></span>Does
                    the proposed work take advantage of unique
                    facilities and capabilities?</li>
                </ul>
                <p style="text-indent: 0.5in; margin: 0px;"> </p>
                <p style="text-indent: 0.5in; margin: 0px;"><br>
                </p>
              </div>
            </div>
            <br>
            <fieldset class="mimeAttachmentHeader"></fieldset>
            <br>
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