<html><body><div style="font-family: arial, helvetica, sans-serif; font-size: 12pt; color: #000000"><div>Dear Pavel,<br></div><div>Good points. Let is take a few minutes tomorrow and go over your ideas.<br data-mce-bogus="1"></div><div>We will have a short meeting tomorrow. It would be good to document<br></div><div>our discussion. Thanks.<br data-mce-bogus="1"></div><div>-H<br data-mce-bogus="1"></div><div><br></div><hr id="zwchr" data-marker="__DIVIDER__"><div data-marker="__HEADERS__"><b>From: </b>"Pavel Degtiarenko" <pavel@jlab.org><br><b>To: </b>"isotope-prod" <isotope-prod@jlab.org><br><b>Sent: </b>Monday, February 27, 2017 10:17:47 AM<br><b>Subject: </b>Re: [Isotope-prod] Cu-67 pricing<br></div><br><div data-marker="__QUOTED_TEXT__"><div class="moz-cite-prefix">Dear All,<br>
<br>
I just wanted to mention that not all options of working with
natural Ga are investigated and rejected. The final choice should
be the result of the overall cost optimization, and weighting of
all pluses and minuses - essentially that should be decided when
the R&D is done, or during the R&D. <br>
<br>
Clearly natural Ga has the advantage of the price and the optimal
size of the target as the result. On the other hand, Ga-71 is a
clear winner for radiological purity and the "undesirables"
production. There is however a gray area that's not investigated
yet. Using natural Ga, and going up in energy from 18.5 MeV, we
should find the beam energy at which the radiological purity is
still "good enough", say, less than 1% of Cu-64 (by the way, is
10% of Cu-64 "good enough"?). At 18.5 MeV it's exact zero, and
it's probably not necessary. <br>
<br>
The same type of the energy optimization question #2: at 18.5 MeV
the production of the major undesirable isotope of Ga-67 is zero.
At what energy its production becomes unacceptably high. What
would be the unacceptably high level of Ga-67 production. I would
argue that having that level at 2-5 times that of Cu-67 wouldn't
be too bad and won't change the handling and separation procedures
dramatically. But may be if it's even a factor of 100, that
wouldn't be that bad either? Such limit should be investigated.<br>
<br>
When we find and verify these energies during the R&D stage,
we should make the choice. May be we could run larger volume
optimized natural Ga target at one of these optimal energies, and
concentrate the design efforts on having a higher beam power, and
thus keep the same production rates of Cu-67 with acceptable
purity, using natural Ga.<br>
<br>
Best regards,<br>
Pavel<br>
<br>
On 2/27/2017 9:19 AM, Hari Areti wrote:<br>
</div>
<blockquote cite="mid:256470525.765633.1488205156991.JavaMail.zimbra@jlab.org">
<div style="font-family: arial, helvetica, sans-serif; font-size:
12pt; color: #000000">
<div>99;8% isotopically pure GA-71 is $3.26/mg.<br>
</div>
<div>-H<br>
</div>
<div><br>
</div>
<hr id="zwchr">
<div><b>From: </b>"George
Kharashvili" <a class="moz-txt-link-rfc2396E" href="mailto:georgek@jlab.org" target="_blank"><georgek@jlab.org></a><br>
<b>To: </b>"isotope-prod" <a class="moz-txt-link-rfc2396E" href="mailto:isotope-prod@jlab.org" target="_blank"><isotope-prod@jlab.org></a><br>
<b>Sent: </b>Friday, February 24, 2017 1:37:14 PM<br>
<b>Subject: </b>[Isotope-prod] Cu-67 pricing<br>
</div>
<br>
<div>
<div style="font-family: arial, helvetica, sans-serif;
font-size: 12pt; color: #000000">
<div>Dear all,<br>
<br>
I requested a Cu-67 quote from Oak Ridge after our meeting
yesterday. I was told that is is not currently available
and may become available in a few months time, which is
when they would give us an official quote. But they kindIy
provided an estimate (not a quote) of $526.00 per mCi of
Cu-67 with a $4,435.00 dispensing/Packaging/Shipment
charger per order.<br>
Below are some details about what they offer for Cu-67. I
would like to point out the radiopurity info: 60% activity
being Cu-64! I believe this is where our method can be
superior: using 40-50 MeV beam on Ga-71 target, we can end
up with virtually no Cu-64 in our final product.<br>
<br>
</div>
<div><img src="cid:part1.BC599B3D.83354983@jlab.org" height="399" width="885"></div>
<br>
<div>--<br>
George Kharashvili<br>
Jefferson Lab Radiation Control<br>
757-269-6435</div>
</div>
<br>
_______________________________________________<br>
Isotope-prod mailing list<br>
<a class="moz-txt-link-abbreviated" href="mailto:Isotope-prod@jlab.org" target="_blank">Isotope-prod@jlab.org</a><br>
<a class="moz-txt-link-freetext" href="https://mailman.jlab.org/mailman/listinfo/isotope-prod" target="_blank">https://mailman.jlab.org/mailman/listinfo/isotope-prod</a><br>
</div>
</div>
<br>
<fieldset class="mimeAttachmentHeader"></fieldset>
<br>
<pre>_______________________________________________
Isotope-prod mailing list
<a class="moz-txt-link-abbreviated" href="mailto:Isotope-prod@jlab.org" target="_blank">Isotope-prod@jlab.org</a>
<a class="moz-txt-link-freetext" href="https://mailman.jlab.org/mailman/listinfo/isotope-prod" target="_blank">https://mailman.jlab.org/mailman/listinfo/isotope-prod</a>
</pre>
</blockquote>
<p><br>
</p>
<br>_______________________________________________<br>Isotope-prod mailing list<br>Isotope-prod@jlab.org<br>https://mailman.jlab.org/mailman/listinfo/isotope-prod<br></div></div></body></html>