[Isotope-prod] Reminder VCU Talk Monday 11:30 CC F224-5

[Pavel Degtiarenko]

Dear All,

Could anyone clarify to us the situation with the toxicity of Copper: 
what ratio of (Cu-63 + Cu-65) to Cu-67 atoms in the final product is too 
big, such that the product would become unacceptable.

We understand now that by making Cu-67 from Gallium, for example, the 
ratio could be done less than an order of few times, or even less than 
one. In case of Zinc target the ratio would be worse because the stable 
isotopes of Zinc are closer in both Z and A to stable Cu-63 and Cu-65 
than the isotopes of Gallium. I guess this ratio would be enormous if 
Cu-67 is produced in Copper with double neutron captures on reactors.

In our conditions, without the initial Copper in the target, the ratio 
should stay rather limited, with the Gallium target having some 
advantage in that respect. Would that be good enough? What would be a 
hard limit on the ratio?

Best regards,
Pavel



On 9/28/2015 5:12 PM, Sundaresan Gobalakrishnan wrote:
>
> Actinium-225 and Copper-67 are the first two products that we could 
> initially try, due to their high medical relevance and in-house 
> availability of related technologies for in vivo delivery in living 
> subjects (in mice for now).
>
> Best regards,
> Sundaresan
>
> On Sep 28, 2015 4:46 PM, "Wells, Douglas P." <Doug.Wells at sdsmt.edu> wrote:
>
>     I wonder if, in the meantime - before the phone call is held, VCU
>     can share with us the list of nuclear species that they are
>     interested in?    We (SDSM&T) could look into photo-production of
>     them if we knew what species are on their mind.
>
>     Thanks---D
>
>     -----Original Message-----
>     From: Isotope-prod [mailto:isotope-prod-bounces at jlab.org] On
>     Behalf Of Sundaresan Gobalakrishnan
>     Sent: Monday, September 28, 2015 7:38 AM
>     To: George Neil; isotope production
>     Subject: Re: [Isotope-prod] Reminder VCU Talk Monday 11:30 CC F224-5
>
>     Dear George and All,
>
>     I regret to inform you that due to an emergency in Dr. Zweit's
>     family, he will not be able to come and present his ideas at JLab
>     today.
>
>     Once he returns to work, he will get in touch with you to
>     reschedule his presentation.
>
>     Very sorry about any inconvenience this may cause.
>
>     Best regards,
>     Sundaresan
>
>     _____________________________________________
>     Sundaresan Gobalakrishnan, PhD
>     Assistant Professor
>     Center for Molecular Imaging, Department of Radiology Virginia
>     Commonwealth University, Richmond, VA - 23298
>     Phone: 804-628-9165; Fax: 804-628-0223
>     E-mail: sundaresan.gobalakrishnan at vcuhealth.org
>
>
>
>     -----Original Message-----
>     From: Isotope-prod [mailto:isotope-prod-bounces at jlab.org] On
>     Behalf Of George Neil
>     Sent: Friday, September 25, 2015 11:39 AM
>     To: isotope production <isotope-prod at jlab.org>
>     Subject: [Isotope-prod] Reminder VCU Talk Monday 11:30 CC F224-5
>
>
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